In a study done by Pharmatech among three groups of male subjects engaged in a weight training program, the two groups that used Belizean Man Vine extract gained lb and lb, respectively, more muscle mass than the placebo group over an eight-week period. The benefits reported, which were universal to all test subjects, are increased muscle mass, improved recovery times and increased strength. What is of particular interest is that group that gained more lb of muscle did so on a diet that consisted of 50% of the calories and protein than that of the group that gained lb, clearly demonstrating the anti-proteolytic action of the extract. It is also likely that the phenylethanoid glycosides can both increase recovery and enhance nitric oxide production (from histamine inhibition) may be contributory factors to the acquired muscle gains.
As a non-aromatizing androgen, dihydrotestosterone is extremely potent. Aromatization refers to the conversion of testosterone or anabolic steroids into estrogen. High estrogenic activity causes bloating, acne, water retention and oily skin. As dihydrotestosterone does not aromatize even at high dosages, users do not face the aforementioned side-effects. Lack of water retention also has a hardening effect on muscle tissue, in bodybuilders. Being a powerful androgen, dihydrotestosterone is also responsible for a shift in the estrogen-testosterone ratio in the body. Due to its predominant androgenic component, the steroid has a stimulating effect on the adreno-pituitary functions, and causes neurological excitation in the ‘sexual orientation areas of the brain’. This in turn, spikes sex drive in males.
The Oxandrolone hormone does not carry any estrogenic related side effects. It does not aromatize and cannot lead to gynecomastia or water retention due to increases in estrogen levels. It further carries no progestin related activity, which again supports no estrogenic related side effects. Due to water retention being impossible with this steroid, this will decrease the risk of high blood pressure. Excess water retention can promote high blood pressure. Some steroids that do not aromatize can lead to high blood pressure, such as Trenbolone , but Anavar is rarely associated with this trait.