It has been reported that the inhibition caused by Methenolone Enanthate (Primobolan Depot) is lesser than that of Deca or testosterone, this is because of the fact that the CNS activities are low, lesser transformation to DHT, and shortage of aromatization to estrogen. Contrasting with Deca, its metabolic activities are not disengaged by 5a-reductase and there are no harm or dangers for skin and hair from this steroid. Nonetheless, when this steroid is used individually for normal dosage, the production of natural testosterone and DHT are inhibited, this can progress and make the skin better if no other anabolic steroids are used with it.
INTERACTIONS WITH OTHER MEDICINES AND OTHER FORMS OF INTERACTION Use of beta-blockers in combination with blockers “slow” calcium channels, has a negative inotropic effect, such as verapamil, diltiazem, can lead to the strengthening of this effect, especially in patients with methenolone enanthate reduced myocardial contractility and / or with impaired sinoatrial or atrioventricular conduction. This may cause severe hypotension, bradycardia and heart failure. Blockers “slow” calcium channel blockers should not be administered intravenously within 48 hours after the cancellation of a beta-blocker. Concomitant therapy with dihydropyridines, eg, nifedipine, may increase the risk of hypotension, patients with latent heart failure may be signs of circulatory disorders. Cardiac glycosides in combination with beta-blockers may increase atrioventricular conduction time. beta-blockers may exacerbate the “rebound” hypertension, which can occur after clonidine. If assigned to both drugs, receiving a beta-blocker should be discontinued for a few days prior to discontinuation of clonidine. If you want to assign a few days after discontinuation of clonidine. It should be used with caution in the beta-blocker in combination with class I antiarrhythmics such as disopyramide (cardiodepressivny stacking). Concomitant use of sympathomimetic agents, eg adrenaline, may counteract the effect of beta blockers (significant increase in blood pressure) Concomitant use of agents which inhibit prostaglandin synthetase (., ibuprofen, indomethacin), can reduce the hypotensive effect of beta blockers. Preparations containing lithium should not be used with diuretics, as they may reduce its renal clearance. caution should be exercised in the application of funds for general anesthesia in combination with Tenoretikom. The anesthetist should be informed about the application Tenoretika and should be chosen anesthetic, has the lowest, as far as possible negative inotropic effect. The use of beta-blockers, together with the means for general methenolone enanthate anesthesia may increase the risk of hypotension. The use of funds for general anesthesia, reducing myocardial contractility, should be avoided. lotofit attrezzi pilates pavigym