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Bodybuilders have been using Caffeine for a long time and have “stacked” it with ephedrine and aspirin for rapid weight loss. This has shown to be effective, but can be very dangerous to the body. Reports have shown them to use a common stack of 200mg Caffeine, 20mg ephedrine, and 150-300 mg of aspirin (also known as an ECA Stack). This stack is usually used for three to four weeks at a time with an off period of one to two weeks. As mentioned before, this is not a safe way to lose weight and should not be used without a doctor’s supervision.


Much of the legislative activity has stemmed from Purdue Pharma’s decision in 2011 to begin a modification of Oxycontin’s composition to make it more difficult to crush for snorting or injecting. The new formulation, OxyNeo, is intended to be preventative in this regard and retain its effectiveness as a painkiller. Since introducing its Narcotics Safety and Awareness Act , Ontario has committed to focusing on drug addiction, particularly in the monitoring and identification of problem opioid prescriptions, as well as the education of patients, doctors, and pharmacists. [76] This Act, introduced in 2010, commits to the establishment of a unified database to fulfil this intention. [77] Both the public and medical community have received the legislation positively, though concerns about the ramifications of legal changes have been expressed. Because laws are largely provincially regulated, many speculate a national strategy is needed to prevent smuggling across provincial borders from jurisdictions with looser restrictions. [78]

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